OP Scientific

Services

Independent scientific consulting in computational systems biology and multi-omics.

Scientific advisory, study design and training

When you want the study to be analysis-ready from day one - or you need a clear plan to triage and salvage an existing dataset.

  • Omics-aware study design: endpoints, confounders, batch strategy, and “what will we conclude if X happens?”
  • Practical power/feasibility input (including what not to do with the sample size you have)
  • Methods + analysis sections for grants/proposals and internal documents
  • Reviewer-response support: targeted re-analysis, sensitivity checks, and figure refits
  • Hands-on training/workshops using your own data and your preferred stack

Typical format: short consults, project “audit” days, or recurring advisory (e.g., 1-2 days/month). Deliverables: a decision-oriented analysis plan, written notes, and (when relevant) training materials.

Multi-omics and spatial data analysis

From raw data to figures and tables you can publish or make decisions from - end-to-end or as a focused module.

  • Bulk RNA-seq; sc/snRNA-seq (QC, annotation, differential states, compositional effects)
  • Spatial transcriptomics (10x Visium / Visium HD: QC, deconvolution/colocalization, region-level biology)
  • LC-MS proteomics / metabolomics (QC, differential abundance, pathway context)
  • Multi-omics integration and network/pathway-level interpretation
  • Reproducible pipelines (Snakemake/containers where they add real portability)

Typical format: a scoped analysis module or full workflow with checkpoints. Deliverables: reproducible code, clean tables, publication-ready figures, and a concise written results narrative aligned to your question.

Translational biomarker and target discovery

For programs that need mechanism, stratification, or actionable signals - not just lists of differentially expressed features.

  • Phenotype-linked signatures and candidate panels designed for follow-up validation
  • Network/module analysis tied to readouts (disease severity, hemodynamics, outcomes)
  • Predictive modeling with clear validation logic and interpretable outputs
  • Target/biomarker prioritization with a transparent rationale and next-step experiments

Typical format: focused discovery sprint or embedded support within a translational program. Deliverables: ranked candidates/panels, model outputs with validation summaries, and concrete next-step recommendations.

How I work

Intake and alignment

  • Scope, success criteria, constraints (timeline, compute, data access), and what decisions the analysis must support

Data audit and analysis plan

  • Quick QC/feasibility readout, then a written plan: contrasts, covariates, validation strategy, and deliverables

Iterative checkpoints

  • Short cycles with visible outputs (figures/tables), decision notes, and course-corrections early rather than late

Delivery and handoff

  • Reproducible repo + walkthrough. You should be able to rerun, extend, and defend the work

Support through submission / follow-up

  • Targeted additions for rebuttals, extra sensitivity checks, and “one more figure” moments